DrugRepV_0001 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | Brazilian strain ZKV2015 | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 29150641 |
DrugRepV_0002 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | Brazilian strain ZKV2015 | NA | NA | Decrease | Approved | 29150641 |
DrugRepV_0003 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | Brazilian strain ZKV2015 | NA | Real-time PCR | Decrease (20 Fold) | Approved | 29150641 |
DrugRepV_0004 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | Brazilian strain ZKV2015 | NA | Immunohistochemical assay | Decrease (10 %) | Approved | 29150641 |
DrugRepV_0005 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | GZ01, a recent Asian lineage | NA | Plaque assay | Decrease (100 %) | Approved | 29033372 |
DrugRepV_0007 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | GZ01, a recent Asian lineage | NA | Plaque assay | Decrease (60 %) | Approved | 29033372 |
DrugRepV_0021 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | GZ01, a recent Asian lineage | NA | Real-time PCR | Decrease (50 %) | Approved | 29033372 |
DrugRepV_0022 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | GZ01, a recent Asian lineage | NA | Real-time PCR | Decrease (50 %) | Approved | 29033372 |
DrugRepV_0023 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | FSS13025 strain (old Asian lineage) | NA | Real-time PCR | Decrease (50 %) | Approved | 29033372 |
DrugRepV_0024 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | GZ01, a recent Asian lineage | NA | Real-time PCR | Decrease (2 Copies (10(6)/ml)) | Approved | 29033372 |
DrugRepV_0025 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | GZ01, a recent Asian lineage | NA | Real-time PCR | Decrease (1 Copies (10(6)/ml)) | Approved | 29033372 |
DrugRepV_0026 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | GZ01, a recent Asian lineage | NA | NA | Decrease | Approved | 29033372 |
DrugRepV_0027 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | GZ01, a recent Asian lineage | NA | Immunohistochemical assay | Decrease (85 %) | Approved | 29033372 |
DrugRepV_0028 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A(H1N1)pdm09 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0029 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A(H3N2) | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0030 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | B (Victoria lineage) | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0031 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | B (Yamagata lineage) | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0032 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A(H1N1)pdm09/A/Sydney/185/2015 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0033 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A(H1N1)pdm09/A/Singapore/TT1275/2015 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0034 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A(H1N1)pdm09/A/Sydney/158/2016 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0035 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A(H1N1)pdm09/A/Victoria/2500/2016 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0036 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A(H1N1)pdm09 /A/Malaysia/2/2014 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0037 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A(H3N2) /A/Victoria/1031/2010 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0038 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A(H3N2) /A/Victoria/1035/2010 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0039 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A(H3N2) /A/Victoria/92/2012 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0040 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A(H3N2) /A/Malaysia/22/2013 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0041 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A(H3N2) /A/Sydney/236/2014 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0042 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | B/ B/South Australia/2/2015 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0043 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | B/ B/Canberra/1/2015 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0044 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | B/ B/South Australia/5/2015 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0045 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | B/ B/Perth/136/2015 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_0102 | Flubendazole | Antiparasitic products, Insectisides and Repellents | Helminthiasis | Zika virus | Mex2-81 | NA | Immunoflourescence assay | Decrease (50 %) | Experimental, Withdrawn | 28099856 |
DrugRepV_0104 | Albendazole | Antiparasitic products, Insectisides and Repellents | Parasitic infections | Zika virus | Mex2-81 | NA | Immunoflourescence assay | No significant effect | Approved | 28099856 |
DrugRepV_0119 | Albendazole | Antiparasitic products, Insectisides and Repellents | Parasitic infections | Zika virus | Mex2-81 | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 28099856 |
DrugRepV_0199 | Chloroquine | Antiparasitic products, Insectisides and Repellents | malaria | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27890675 |
DrugRepV_0201 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational | 27890675 |
DrugRepV_0210 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOLA/Mayinga-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational | 27890675 |
DrugRepV_0317 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational, Vet approved | 27622822 |
DrugRepV_0318 | Mebendazole | Antiparasitic products, Insectisides and Repellents | Helminthiasis (Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections) | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Vet approved | 27622822 |
DrugRepV_0325 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0326 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0327 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0338 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0339 | Mebendazole | Antiparasitic products, Insectisides and Repellents | Helminthiasis (Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections) | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved, Vet approved | 27622822 |
DrugRepV_0345 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0346 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0347 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0355 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Ebola Zaire | NA | Survival assay | Increase | Approved | 27622822 |
DrugRepV_0356 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0358 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0367 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Ebola Mayinga | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0393 | Mebendazole | Antiparasitic products, Insectisides and Repellents | Helminthiasis (Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections) | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Vet approved | 26041706 |
DrugRepV_0397 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0400 | Pentamidine | Antiparasitic products, Insectisides and Repellents | Pneumonia | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0405 | Pyrvinium Pamoate | Antiparasitic products, Insectisides and Repellents | Pinworm infestations | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0423 | Atovaquone | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0479 | Atovaquone | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOV-VLP | NA | Flow cytometry | No significant effect | Approved | 26041706 |
DrugRepV_0535 | Mebendazole | Antiparasitic products, Insectisides and Repellents | Helminthiasis (Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections) | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Vet approved | 26038505 |
DrugRepV_0538 | Albendazole | Antiparasitic products, Insectisides and Repellents | Parasitic infections | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0548 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0550 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26038505 |
DrugRepV_0558 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0572 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0574 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Crimean-Congo hemorrhagic fever virus | IbAr10200, Nigeria | NA | Plaque assay | Decrease (50 %) | Approved | 25796972 |
DrugRepV_0575 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Crimean-Congo hemorrhagic fever virus | ArD39554 | NA | Plaque assay | Decrease (50 %) | Approved | 25796972 |
DrugRepV_0576 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Crimean-Congo hemorrhagic fever virus | IbAr10200, Nigeria | NA | Plaque assay | Decrease (50 %) | Approved | 25796972 |
DrugRepV_0606 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Lassa virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (51 %) | Approved | 23577127 |
DrugRepV_0609 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Lassa virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (34 %) | Approved | 23577127 |
DrugRepV_0629 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Lassa virus | Josiah | NA | Real-time PCR | No significant effect | Approved | 23577127 |
DrugRepV_0632 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Lassa virus | Josiah | NA | Real-time PCR | No significant effect | Approved | 23577127 |
DrugRepV_0645 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (97 %) | Approved | 23577127 |
DrugRepV_0648 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (97 %) | Approved | 23577127 |
DrugRepV_0669 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (99 %) | Approved | 23577127 |
DrugRepV_0672 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (97 %) | Approved | 23577127 |
DrugRepV_0692 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved | 23577127 |
DrugRepV_0695 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | Decrease | Approved | 23577127 |
DrugRepV_0709 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0710 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | GP derived Pseudovirus | NA | Luciferase virus entry activity | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0711 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0713 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | Musoke | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0714 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | Musoke | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0715 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | Musoke | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0717 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0718 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0719 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0721 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0722 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0723 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0726 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | ma-EBOV | NA | NA | Increase | Approved | 23577127 |
DrugRepV_0764 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (99.52 %) | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_0765 | Mefloquine Hydrochloride | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (99.815 %) | Approved, Investigational | 27476412 |
DrugRepV_0781 | Pyrimethamine | Antiparasitic products, Insectisides and Repellents | Toxoplasmosis | Acute malaria | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (83.105 %) | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_0801 | Mebendazole | Antiparasitic products, Insectisides and Repellents | Helminthiasis (Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections) | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (71.81 %) | Approved, Vet approved | 27476412 |
DrugRepV_0814 | Albendazole | Antiparasitic products, Insectisides and Repellents | Parasitic infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (68.09 %) | Approved | 27476412 |
DrugRepV_0827 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (65.085 %) | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_0836 | Primaquine Phosphate | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (61.24 %) | Approved | 27476412 |
DrugRepV_0838 | Pentamidine Isethionate | Antiparasitic products, Insectisides and Repellents | Pneumonia | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (60.63 %) | Approved, Investigational | 27476412 |
DrugRepV_0969 | Praziquantel | Antiparasitic products, Insectisides and Repellents | Schistosomiasis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (54.16 %) | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_0970 | Atovaquone | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (53.93 %) | Approved | 27476412 |
DrugRepV_1040 | Chloroquine Diphosphate | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (59.115 %) | Approved | 27476412 |
DrugRepV_1188 | Lindane | Antiparasitic products, Insectisides and Repellents | Scabies | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.465 %) | Approved, Withdrawn | 27476412 |
DrugRepV_1215 | Metronidazole | Antiparasitic products, Insectisides and Repellents | Amebiasis | Vaginitis | Trichomonas infections | Giardiasis | Anaerobic bacteria | Treponemal infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (48.465 %) | Approved | 27476412 |
DrugRepV_1241 | Malathion | Antiparasitic products, Insectisides and Repellents | Pediculus humanus capitis of the scalp hair | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (49.575 %) | Approved, Investigational | 27476412 |
DrugRepV_1320 | Hydroxychloroquine Sulfate | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (43.595 %) | Approved | 27476412 |
DrugRepV_1368 | Quinine Hydrochloride Hydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Leg cramps | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (47.065 %) | Approved | 27476412 |
DrugRepV_1406 | Permethrin | Antiparasitic products, Insectisides and Repellents | Scabies | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (42.93 %) | Approved, Investigational | 27476412 |
DrugRepV_1409 | Artemether | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (42.96 %) | Approved | 27476412 |
DrugRepV_1535 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Zika virus | MEX_I_7 | NA | Flow cytometry | Decrease (50 %) | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_1536 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | MEX_I_7 | NA | Flow cytometry | Decrease (50 %) | Approved, Investigational | 27476412 |
DrugRepV_1544 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Zika virus | MEX_I_7 | NA | Flow cytometry | No significant effect (50 %) | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_1546 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | MEX_I_7 | NA | Flow cytometry | Increase (200 %) | Approved, Investigational | 27476412 |
DrugRepV_1549 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Zika virus | DAK_41525 | NA | Flow cytometry | Decrease (60 %) | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_1551 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | DAK_41525 | NA | Flow cytometry | Increase (120 %) | Approved, Investigational | 27476412 |
DrugRepV_1554 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_1555 | Pyrimethamine | Antiparasitic products, Insectisides and Repellents | Toxoplasmosis | Acute malaria | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | No significant effect | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_1560 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 27476412 |
DrugRepV_1572 | Fenbendazole | Antiparasitic products, Insectisides and Repellents | Helminthiasis | Rift Valley fever virus | MP12-Luc | NA | Luciferase reporter assay | Decrease (81 %) | Vet approved | 26217313 |
DrugRepV_1573 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Rift Valley fever virus | MP12-Luc | NA | Luciferase reporter assay | Decrease (57 %) | Approved, Investigational, Vet approved | 26217313 |
DrugRepV_1616 | Pyronaridine tetraphosphate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Recombinant, infectious Ebola virus encoding green fluorescent protein | NA | Cell based assay | Decrease (50 %) | Approved | 26834994 |
DrugRepV_1618 | Chloroquine Diphosphate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Recombinant, infectious Ebola virus encoding green fluorescent protein | NA | Cell based assay | Decrease (50 %) | Approved | 26834994 |
DrugRepV_1653 | Tenonitrozole | Antiparasitic products, Insectisides and Repellents | Protozoal infections | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Experimental | 27571349 |
DrugRepV_1655 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | MR766 | NA | Cell viability assay | Decrease (53.6 %) | Approved, Investigational, Vet approved | 27571349 |
DrugRepV_1694 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | MR766 | NA | Cell viability assay | Decrease (51.2 %) | Approved | 27571349 |
DrugRepV_1724 | Tenonitrozole | Antiparasitic products, Insectisides and Repellents | Protozoal infections | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Experimental | 27571349 |
DrugRepV_1726 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | MR766 | NA | Cell viability assay | Decrease (62.1 %) | Approved, Investigational, Vet approved | 27571349 |
DrugRepV_1765 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | MR766 | NA | Cell viability assay | Decrease (97.3 %) | Approved | 27571349 |
DrugRepV_1795 | Tenonitrozole | Antiparasitic products, Insectisides and Repellents | Protozoal infections | Zika virus | MR766 | NA | Cell viability assay | No significant effect | Experimental | 27571349 |
DrugRepV_1797 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | MR766 | NA | Cell viability assay | No significant effect | Approved, Investigational, Vet approved | 27571349 |
DrugRepV_1836 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | MR766 | NA | Cell viability assay | No significant effect | Approved | 27571349 |
DrugRepV_1868 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | NA | NA | Cell viability assay | Decrease (50 %) | Approved | 27571349 |
DrugRepV_1869 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | NA | NA | Cell viability assay | Decrease (50 %) | Approved | 27571349 |
DrugRepV_1878 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | Approved | 27571349 |
DrugRepV_1879 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | Approved | 27571349 |
DrugRepV_1881 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Enzyme-linked immunosorbent assay | Decrease | Approved | 27571349 |
DrugRepV_1883 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Plaque assay | Decrease (50 %) | Approved | 27571349 |
DrugRepV_1884 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | FSS13025 | NA | Real-time PCR | Decrease (50 %) | Approved | 27571349 |
DrugRepV_1886 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | FSS13025 | NA | Real-time PCR | Decrease | Approved | 27571349 |
DrugRepV_1888 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | Approved | 27571349 |
DrugRepV_1889 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | Approved | 27571349 |
DrugRepV_1910 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | PLCal_ZV | NA | MTT assay | Decrease (50 %) | Approved | 29315671 |
DrugRepV_1911 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | PLCal_ZV | NA | MTT assay | Decrease (50 %) | Approved | 29315671 |
DrugRepV_1913 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | PLCal_ZV | NA | Plaque assay | Decrease (50 %) | Approved | 29315671 |
DrugRepV_1914 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | PLCal_ZV | NA | Plaque assay | Decrease (50 %) | Approved | 29315671 |
DrugRepV_1916 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | PLCal_ZV | NA | Time of addition assay | Decrease (50 %) | Approved | 29315671 |
DrugRepV_1917 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | PLCal_ZV | NA | Time of addition assay | Decrease (62.5 %) | Approved | 29315671 |
DrugRepV_1919 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | PLCal_ZV | NA | Real-time PCR | Decrease (85.7 %) | Approved | 29315671 |
DrugRepV_1920 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | PLCal_ZV | NA | Real-time PCR | Decrease (99 %) | Approved | 29315671 |
DrugRepV_1922 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | PLCal_ZV | NA | MTT assay | Decrease (65 %) | Approved | 29315671 |
DrugRepV_1923 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | PLCal_ZV | NA | MTT assay | Decrease (70 %) | Approved | 29315671 |
DrugRepV_1941 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | SZ-WIV01 | NA | Plaque assay | Decrease (>100 Fold) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1942 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | SZ-WIV01 | NA | Immunoflourescence assay | Decrease (100 %) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1943 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | SZ-WIV01 | NA | Western blot | Decrease (100 Band Intensity) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1944 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease (98 %) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1945 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1946 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease (100 %) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1947 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1948 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease (100 %) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1949 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease (100 %) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1950 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease (98 %) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1951 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease (100 %) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1952 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Zika virus | SZ-WIV01 | NA | Plaque assay | Decrease (100 %) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1953 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Zika virus | SZ-WIV01 | NA | Immunoflourescence assay | Decrease (100 %) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1954 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Zika virus | SZ-WIV01 | NA | Western blot | Decrease (100 Band Intensity) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1955 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease (98 %) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1956 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1957 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1958 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1959 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1960 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease (100 %) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1961 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease (100 %) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1962 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease (98 %) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1963 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Zika virus | SZ-WIV01 | NA | Real-time PCR | Decrease (100 %) | Approved, Investigational, Vet approved | 28480282 |
DrugRepV_1967 | Emetine Dihydrochloride Hydrate | Antiparasitic products, Insectisides and Repellents | Protozoal disease | Middle East respiratory syndrome coronavirus | Jordan | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | NA | 24841273 |
DrugRepV_1968 | Chloroquine Diphosphate | Antiparasitic products, Insectisides and Repellents | Parasitic infections | Middle East respiratory syndrome coronavirus | Jordan | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_1969 | Hydroxychloroquine Sulfate | Antiparasitic products, Insectisides and Repellents | Malaria | Middle East respiratory syndrome coronavirus | Jordan | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_1970 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Middle East respiratory syndrome coronavirus | Jordan | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved, Investigational | 24841273 |
DrugRepV_1971 | Amodiaquine Dihydrochloride Dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Middle East respiratory syndrome coronavirus | Jordan | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved, Investigational | 24841273 |
DrugRepV_1992 | Emetine Dihydrochloride Hydrate | Antiparasitic products, Insectisides and Repellents | Protozoal disease | Middle East respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24841273 |
DrugRepV_1993 | Chloroquine Diphosphate | Antiparasitic products, Insectisides and Repellents | Parasitic infections | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_1994 | Hydroxychloroquine Sulfate | Antiparasitic products, Insectisides and Repellents | Malaria | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 24841273 |
DrugRepV_1995 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 24841273 |
DrugRepV_1996 | Amodiaquine Dihydrochloride dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 24841273 |
DrugRepV_2026 | Artemisinin | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Experimental | 26585243 |
DrugRepV_2035 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Middle East respiratory syndrome coronavirus | EMC/2012 | NA | Cell viability assay | Decrease (50 %) | Approved | 24841269 |
DrugRepV_2039 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Severe acute respiratory syndrome coronavirus | NA | NA | Cell viability assay | Decrease (50 %) | Approved | 24841269 |
DrugRepV_2043 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Severe acute respiratory syndrome coronavirus | 229E-GFP | NA | Cell viability assay | Decrease (50 %) | Approved | 24841269 |
DrugRepV_2051 | Pyrimethamine | Antiparasitic products, Insectisides and Repellents | Toxoplasmosis | Acute malaria | Middle East respiratory syndrome coronavirus | EMC/2012 | NA | Cell viability assay | No significant decrease (20 %) | Approved, Investigational, Vet approved | 24841269 |
DrugRepV_2054 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Chikungunya virus | S27 | NA | Real-time PCR | Decrease (50 %) | Approved | 27742486 |
DrugRepV_2055 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Chikungunya virus | S27 | NA | Real-time PCR | Decrease (50 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2056 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Chikungunya virus | S27 | NA | Immunoflourescence assay | Decrease | Approved | 27742486 |
DrugRepV_2057 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Chikungunya virus | S27 | NA | Immunoflourescence assay | Decrease | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2058 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Chikungunya virus | 0611aTw | NA | Real-time PCR | Decrease (50 %) | Approved | 27742486 |
DrugRepV_2059 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Chikungunya virus | 0611aTw | NA | Real-time PCR | Decrease (50 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2060 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Chikungunya virus | 081bTw | NA | Real-time PCR | Decrease (50 %) | Approved | 27742486 |
DrugRepV_2061 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Chikungunya virus | 081bTw | NA | Real-time PCR | Decrease (50 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2062 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Chikungunya virus | S27 | NA | Real-time PCR | Decrease (50 %) | Approved | 27742486 |
DrugRepV_2063 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Chikungunya virus | S27 | NA | Real-time PCR | Decrease (50 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2066 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Severe acute respiratory syndrome coronavirus | NA | NA | Immunoblot assay | Decrease | Approved | 15215127 |
DrugRepV_2067 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Severe acute respiratory syndrome coronavirus | NA | NA | Immunoflourescence assay | Decrease | Approved | 15215127 |
DrugRepV_2068 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease | Approved | 15215127 |
DrugRepV_2156 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Decrease (96.1181392 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2161 | Atovaquone | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Decrease (55.760271 %) | Approved | 27742486 |
DrugRepV_2187 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (12.5546344 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2249 | Praziquantel | Antiparasitic products, Insectisides and Repellents | Schistosomiasis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (5.93918289 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2257 | Pyrimethamine | Antiparasitic products, Insectisides and Repellents | Toxoplasmosis | Acute malaria | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (5.73171647 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2304 | Levamisole Hydrochloride | Antiparasitic products, Insectisides and Repellents | Helminthiasis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (4.33501607 %) | Approved, Investigational, Vet approved, Withdrawn | 27742486 |
DrugRepV_2416 | Artemisinin | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (1.94527744 %) | Experimental | 27742486 |
DrugRepV_2502 | Meglumine | Antiparasitic products, Insectisides and Repellents | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (0.08526202 %) | Approved | 27742486 |
DrugRepV_2508 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Decrease (100 %) | Approved | 27742486 |
DrugRepV_2528 | Artemether | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.4769483 %) | Approved | 27742486 |
DrugRepV_2550 | Albendazole | Antiparasitic products, Insectisides and Repellents | Parasitic infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.8595872 %) | Approved | 27742486 |
DrugRepV_2555 | Flubendazole | Antiparasitic products, Insectisides and Repellents | Helminthiasis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.9381124 %) | Experimental, Withdrawn | 27742486 |
DrugRepV_2580 | Quinine Hydrochloride dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Leg cramps | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.3590955 %) | Approved | 27742486 |
DrugRepV_2702 | Metronidazole | Antiparasitic products, Insectisides and Repellents | Amebiasis | Vaginitis | Trichomonas infections | Giardiasis | Anaerobic bacteria | Treponemal infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.9895213 %) | Approved | 27742486 |
DrugRepV_2738 | Fenbendazole | Antiparasitic products, Insectisides and Repellents | Helminthiasis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-3.5894807 %) | Vet approved | 27742486 |
DrugRepV_2832 | Ornidazole | Antiparasitic products, Insectisides and Repellents | Elective Colorectal Surgery | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-5.9457143 %) | Investigational | 27742486 |
DrugRepV_2936 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Neutral red uptake assay | Decrease (50 %) | Approved | 20336760 |
DrugRepV_2937 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Neutral red uptake assay | Decrease (50 %) | Approved | 20336760 |
DrugRepV_2938 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Neutral red uptake assay | Decrease (50 %) | Approved | 20336760 |
DrugRepV_2939 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Neutral red uptake assay | Decrease (90 %) | Approved | 20336760 |
DrugRepV_2940 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Neutral red uptake assay | Decrease (90 %) | Approved | 20336760 |
DrugRepV_2941 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Neutral red uptake assay | Decrease (90 %) | Approved | 20336760 |
DrugRepV_2942 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Plaque assay | Decrease (3 logs) | Approved | 20336760 |
DrugRepV_2943 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Plaque assay | Decrease (3 logs) | Approved | 20336760 |
DrugRepV_2944 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Plaque assay | Decrease (3 logs) | Approved | 20336760 |
DrugRepV_2945 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Plaque assay | Decrease (94 %) | Approved | 20336760 |
DrugRepV_2946 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Plaque assay | Decrease (65 %) | Approved | 20336760 |
DrugRepV_2947 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Plaque assay | Decrease (70 %) | Approved | 20336760 |
DrugRepV_2948 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Real-time PCR | Decrease | Approved | 20336760 |
DrugRepV_2949 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Real-time PCR | Decrease | Approved | 20336760 |
DrugRepV_2950 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Real-time PCR | Decrease | Approved | 20336760 |
DrugRepV_2951 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | DRDE-06 | NA | Immunoflourescence assay | Decrease | Approved | 20336760 |
DrugRepV_3040 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | LR2006 OPY1 | NA | Luciferase reporter assay | Decrease (50 %) | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3045 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | LR2006 OPY1 | NA | Luciferase reporter assay | Decrease (50 %) | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3049 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | CHIKV-Rluc | NA | Luciferase reporter assay | Decrease (100 %) | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3058 | Atovaquone | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | CHIKV-Rluc | NA | Luciferase reporter assay | Decrease (20 %) | Approved | 26752081 |
DrugRepV_3059 | Triclabendazole | Antiparasitic products, Insectisides and Repellents | Fascioliasis (Parasitic infection) | Chikungunya virus | CHIKV-Rluc | NA | Luciferase reporter assay | Decrease (20 %) | Approved, Investigational | 26752081 |
DrugRepV_3067 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | CHIKV-Rluc | NA | Northern blot | Decrease | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3070 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3071 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3074 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3075 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3081 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | CHIKV-Rluc | NA | Plaque assay | Decrease (3.5 Log) | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3084 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | NA | NA | Plaque assay | Decrease (3 Log) | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3087 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Chikungunya virus | NA | NA | Plaque assay | Decrease (0.2 Log) | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_3102 | Emetine Dihydrochloride | Antiparasitic products, Insectisides and Repellents | Protozoal disease | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (99.5 %) | NA | 23275491 |
DrugRepV_3317 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Cryptosporidiosis and Giardiasis | Influenza virus | B/Brisbane/46/2015 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_3318 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Cryptosporidiosis and Giardiasis | Influenza virus | B/Sydney/39/2014 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_3319 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Cryptosporidiosis and Giardiasis | Influenza virus | A/Perth/265/2009 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_3320 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Cryptosporidiosis and Giardiasis | Influenza virus | A/Osaka/180/2009 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_3321 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Cryptosporidiosis and Giardiasis | Influenza virus | A/New Caledonia/104/2014 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_3322 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Cryptosporidiosis and Giardiasis | Influenza virus | A/Newcastle/22/2014 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_3372 | Pyrimethamine | Antiparasitic products, Insectisides and Repellents | Toxoplasmosis | Acute malaria | Influenza virus | A/ WSN/1933 (H1N1) | | High-throughput screening | Decrease (50 %) | Approved, Investigational, Vet approved | 24096239 |
DrugRepV_3373 | Emetine | Antiparasitic products, Insectisides and Repellents | Protozoal disease | Influenza virus | A/ WSN/1933 (H1N1) | | High-throughput screening | Decrease (50 %) | Experimental | 24096239 |
DrugRepV_3515 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A/Ohio/88/2012 | | Virus yield reduction assay | Decrease (90 %) | Approved, Investigational, Vet approved | 24449767 |
DrugRepV_3516 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A/Ohio/83/2012 | | Virus yield reduction assay | Decrease (90 %) | Approved, Investigational, Vet approved | 24449767 |
DrugRepV_3517 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A/Washington/01/2007 | | Virus yield reduction assay | Decrease (90 %) | Approved, Investigational, Vet approved | 24449767 |
DrugRepV_3518 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A/Texas/12/2007 | | Virus yield reduction assay | Decrease (90 %) | Approved, Investigational, Vet approved | 24449767 |
DrugRepV_3519 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Influenza virus | A/California/04/2009 | | Virus yield reduction assay | Decrease (90 %) | Approved, Investigational, Vet approved | 24449767 |
DrugRepV_3588 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 30149038 |
DrugRepV_3709 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | NA | NA | NA | Decrease (99.9 %) | Approved | 24713118 |
DrugRepV_4031 | Praziquantel | Antiparasitic products, Insectisides and Repellents | Schistosomiasis | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Approved, Investigational, Vet approved | 20668647 |
DrugRepV_4046 | Praziquantel | Antiparasitic products, Insectisides and Repellents | Schistosomiasis | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Approved, Investigational, Vet approved | 20668647 |
DrugRepV_4092 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Mayinga | NA | Inhibition assay | Decrease (50 %) | Approved | 26069727 |
DrugRepV_4093 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Bundibugyo | NA | Inhibition assay | Decrease (50 %) | Approved | 26069727 |
DrugRepV_4095 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Influenza virus | A/turkey/ England/50-92/91 | | Inhibition assay | Decrease (50 %) | Approved | 26069727 |
DrugRepV_4219 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 25970561 |
DrugRepV_4295 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | Approved | 29499487 |
DrugRepV_4296 | Piperazine | Antiparasitic products, Insectisides and Repellents | Parasitic infections (Ascariasis) | Chikungunya virus | DRDE-07 | NA | Immunoflourescence assay | Decrease | Approved, Vet approved | 28842264 |
DrugRepV_4297 | Piperazine | Antiparasitic products, Insectisides and Repellents | Parasitic infections (Ascariasis) | Chikungunya virus | DRDE-07 | NA | Plaque reduction assay | Decrease (81 %) | Approved, Vet approved | 28842264 |
DrugRepV_4712 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | MR766 | NA | Plaque assay | Decrease (50 %) | Approved, Investigational | 27889529 |
DrugRepV_4716 | Amodiaquine Dihydrochloride | Antiparasitic products, Insectisides and Repellents | Malaria | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 29795047 |
DrugRepV_4717 | Amodiaquine Dihydrochloride Dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 29795047 |
DrugRepV_4718 | Chloroquine Diphosphate | Antiparasitic products, Insectisides and Repellents | Parasitic infections | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational, Vet approved | 29795047 |
DrugRepV_4719 | Hydroxychloroquine Sulfate | Antiparasitic products, Insectisides and Repellents | Malaria | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 29795047 |
DrugRepV_4727 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Middle East respiratory syndrome coronavirus | Jordan | NA | Immunoflourescence assay | No significant effect | Approved | 29566060 |
DrugRepV_5083 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Crimean-Congo hemorrhagic fever virus | 86-07 | NA | Plaque assay | Decrease (50 %) | Approved | 25796972 |
DrugRepV_5084 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Crimean-Congo hemorrhagic fever virus | 86-07 | NA | Plaque assay | Decrease (50 %) | Approved | 25796972 |
DrugRepV_5087 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Crimean-Congo hemorrhagic fever virus | 87-07 | NA | Plaque assay | Decrease (50 %) | Approved | 25796972 |
DrugRepV_5177 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Rift Valley fever virus | MP12 | NA | Fluorescence-based assay | Decrease (1 log Resazurin fluorescence) | Investigational | 25267680 |
DrugRepV_5178 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Rift Valley fever virus | MP12 | NA | Plaque assay | Decrease | Investigational | 25267680 |
DrugRepV_5179 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Rift Valley fever virus | MP12 | NA | Plaque assay | Decrease (50 %) | Investigational | 25267680 |
DrugRepV_5212 | Suramin Sodium | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Rift Valley fever virus | NA | NA | RVFV nucleocapsid (N) protein RNA-binding activity | Decrease (50 %) | Investigational | 22644268 |
DrugRepV_5395 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Lassa virus | Josiah | NA | Luciferase assay | Decrease (50 %) | Approved | 30700611 |
DrugRepV_5396 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Mayinga | NA | Luciferase assay | Decrease (50 %) | Approved | 30700611 |
DrugRepV_5397 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Lassa virus | Josiah | NA | Luciferase assay | Decrease (50 %) | Approved | 30700611 |
DrugRepV_5398 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Ebola virus | Mayinga | NA | Luciferase assay | Decrease (50 %) | Approved | 30700611 |
DrugRepV_5409 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | PLCal_ZV | NA | MTT assay | Decrease (50 %) | Approved | 30801742 |
DrugRepV_5412 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | MR 766 | NA | MTT assay | Decrease (50 %) | Approved | 30801742 |
DrugRepV_5415 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | PRVABC59 | NA | MTT assay | Decrease (50 %) | Approved | 30801742 |
DrugRepV_5454 | Atovaquone | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | MR766 | NA | Plaque assay | Decrease (2 log10PFU/ml) | Approved | 30894466 |
DrugRepV_5455 | Atovaquone | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | MR766 | NA | Plaque assay | Decrease (5.5 log10PFU/ml) | Approved | 30894466 |
DrugRepV_5456 | Atovaquone | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | MR766 | NA | Plaque assay | Decrease (2 log10PFU/ml) | Approved | 30894466 |
DrugRepV_5457 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Influenza virus | A/Sydney/185/2015 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_5458 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Influenza virus | A/Singapore/TT1275/2015 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_5459 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Influenza virus | A/Sydney/158/2016 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_5460 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Influenza virus | A/Victoria/2500/2016 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_5461 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Influenza virus | A/Malaysia/2/2014 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_5462 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Influenza virus | A/Victoria/1031/2010 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_5463 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Influenza virus | A/Victoria/1035/2010 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_5464 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Influenza virus | A/Victoria/92/2012 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_5465 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Influenza virus | A/Malaysia/22/2013 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_5466 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Influenza virus | A/Sydney/236/2014 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_5467 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Influenza virus | B/South Australia/2/2015 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_5468 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Influenza virus | B/Canberra/1/2015 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_5469 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Influenza virus | B/South Australia/5/2015 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_5470 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Influenza virus | B/Perth/136/2015 | | Focus forming reduction assay | Decrease (50 %) | Approved, Investigational, Vet approved | 28986103 |
DrugRepV_5474 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | nCoV- 2019BetaCoV/Wuhan/WIV04/2019 | NA | qRT-PCR | Decrease (50 %) | Approved | 32020029 |
DrugRepV_5476 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | SARS Coronavirus-2 | nCoV- 2019BetaCoV/Wuhan/WIV04/2019 | NA | qRT-PCR | Decrease (50 %) | Approved, Investigational, Vet approved | 32020029 |
DrugRepV_5480 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Zika virus | (Asian/Cook Islands/2014 | NA | Plaque assay | Decrease (50 %) | Approved, Investigational, Vet approved | 32135219 |
DrugRepV_5481 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Zika virus | (Asian/Cook Islands/2014 | NA | RT-qPCR | Decrease (50 %) | Approved, Investigational, Vet approved | 32135219 |
DrugRepV_5490 | Primaquine Diphosphate | Antiparasitic products, Insectisides and Repellents | Malaria | Zika virus | PRVABC59 | NA | Cell viability assay | Decrease (50 %) | Approved | 31669333 |
DrugRepV_5491 | Amodiaquine Dihydrochloride Dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Approved, Investigational | 31882748 |
DrugRepV_5492 | Amodiaquine Dihydrochloride Dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Approved, Investigational | 31882748 |
DrugRepV_5493 | Amodiaquine Dihydrochloride Dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Approved, Investigational | 31882748 |
DrugRepV_5494 | Artesunate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Approved, Investigational | 31882748 |
DrugRepV_5505 | Mefloquine hydrochloride | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | GX_P2V/pangolin/2017/Guangxi | NA | qRT-PCR | Decrease | Approved, Investigational | 32149769 |
DrugRepV_5574 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | Approved | 32353859 |
DrugRepV_5773 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Dengue virus | Singapore isolates | | Plaque assay | Decrease (82 %) | Approved | 25251726 |
DrugRepV_5806 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Dengue virus | NA | | Immunoflourescence assay | Decrease (84.62 %) | Approved, Investigational, Vet approved | 22155902 |
DrugRepV_5881 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (78 %) | Approved | 24680954 |
DrugRepV_5882 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (58 %) | Approved | 24680954 |
DrugRepV_5883 | Chloroquine ethyl phenyl Mustard | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (> 99 %) | NA | 24680954 |
DrugRepV_5884 | Chloroquine Mustard | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (> 99 %) | NA | 24680954 |
DrugRepV_5885 | Chloroquine Pamoate | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_5886 | Chloroquine Sulfate | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (30 %) | NA | 24680954 |
DrugRepV_5888 | Primaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | No significant effect (0 %) | Approved | 24680954 |
DrugRepV_5889 | Quinine Hydrobromide Hydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Leg cramps | Dengue virus | NA | | Plaque assay | Decrease (38 %) | NA | 24680954 |
DrugRepV_5891 | Amodiaquine derivative (AQD1) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (90 %) | NA | 24680954 |
DrugRepV_5892 | Amodiaquine derivative (AQD2) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (70 %) | NA | 24680954 |
DrugRepV_5893 | Amodiaquine derivative (AQD3) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (100 %) | NA | 24680954 |
DrugRepV_5894 | Amodiaquine derivative (AQD4) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (100 %) | NA | 24680954 |
DrugRepV_5895 | Amodiaquine derivative (AQD5) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (20 %) | NA | 24680954 |
DrugRepV_5896 | Amodiaquine derivative (AQD6) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (100 %) | NA | 24680954 |
DrugRepV_5897 | Amodiaquine derivative (AQD7) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (97 %) | NA | 24680954 |
DrugRepV_5898 | Amodiaquine derivative (AQD8) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | No significant effect (0 %) | NA | 24680954 |
DrugRepV_5899 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | Approved | 24680954 |
DrugRepV_5900 | Amodiaquine derivative (AQD1) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_5901 | Amodiaquine derivative (AQD2) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_5902 | Amodiaquine derivative (AQD3) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_5903 | Amodiaquine derivative (AQD4) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_5904 | Amodiaquine derivative (AQD5) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_5905 | Amodiaquine derivative (AQD6) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_5906 | Amodiaquine derivative (AQD7) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_5907 | Amodiaquine derivative (AQD8) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_5909 | Chloroquine Mustard | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_5910 | Chloroquine ethyl phenyl Mustard | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_5911 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | Approved | 24680954 |
DrugRepV_5912 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | Approved | 24680954 |
DrugRepV_5913 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | Approved | 24680954 |
DrugRepV_5914 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Real-time PCR | Decrease (90 %) | Approved | 24680954 |
DrugRepV_5915 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Real-time PCR | Decrease (90 %) | Approved | 24680954 |
DrugRepV_5916 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (98 %) | Approved | 24680954 |
DrugRepV_5917 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (90 %) | Approved | 24680954 |
DrugRepV_5918 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (90 %) | Approved | 24680954 |
DrugRepV_5919 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (100 %) | Approved | 24680954 |
DrugRepV_5920 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (80 %) | Approved | 24680954 |
DrugRepV_5921 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (100 %) | Approved | 24680954 |
DrugRepV_5922 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | No significant effect | Approved | 24680954 |
DrugRepV_5923 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (2 Fold) | Approved | 24680954 |
DrugRepV_5924 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (3 Fold) | Approved | 24680954 |
DrugRepV_5925 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (90 %) | Approved | 24680954 |
DrugRepV_5926 | Amodiaquine derivative (AQD8) | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (90 %) | NA | 24680954 |
DrugRepV_5927 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (90 %) | Approved | 24680954 |
DrugRepV_5928 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (90 %) | Approved | 24680954 |
DrugRepV_5970 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | New Guinea | | Plaque assay | Decrease | Approved | 24773578 |
DrugRepV_5971 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | New Guinea | | Real-time PCR | Decrease | Approved | 24773578 |
DrugRepV_5972 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | New Guinea | | Immunoflourescence assay | Decrease | Approved | 24773578 |
DrugRepV_5973 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | New Guinea | | Plaque assay | Decrease | Approved | 25664975 |
DrugRepV_6037 | Quinine sulfate | Antiparasitic products, Insectisides and Repellents | Malaria | Leg cramps | Dengue virus | 16681 | | Focus forming assay | Decrease (81 %) | NA | 30055216 |
DrugRepV_6122 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Dengue virus | NA | | Plaque assay | Decrease (50 %) | Approved, Investigational | 27889529 |
DrugRepV_6314 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Dengue virus | NGC | | Flow cytometry | Decrease (92 %) | Investigational | 16309754 |
DrugRepV_6319 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (84.62 %) | Approved, Investigational, Vet approved | 22155902 |
DrugRepV_7059 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (98 %) | Approved | 24680954 |
DrugRepV_7060 | Primaquine | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (20 %) | Approved | 24680954 |
DrugRepV_7061 | Chloroquine ethyl phenyl Mustard | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (> 99 %) | NA | 24680954 |
DrugRepV_7062 | Chloroquine Mustard | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (> 99 %) | NA | 24680954 |
DrugRepV_7063 | Chloroquine Pamoate | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (10 %) | NA | 24680954 |
DrugRepV_7064 | Chloroquine Sulfate | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | No significant effect (0 %) | NA | 24680954 |
DrugRepV_7066 | Primaquine | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | No significant effect (0 %) | Approved | 24680954 |
DrugRepV_7067 | Quinine Hydrobromide Hydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Leg cramps | West Nile virus | NA | | Plaque assay | No significant effect (0 %) | NA | 24680954 |
DrugRepV_7069 | Amodiaquine derivative (AQD1) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (98 %) | NA | 24680954 |
DrugRepV_7070 | Amodiaquine derivative (AQD2) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_7071 | Amodiaquine derivative (AQD3) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (100 %) | NA | 24680954 |
DrugRepV_7072 | Amodiaquine derivative (AQD4) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (100 %) | NA | 24680954 |
DrugRepV_7073 | Amodiaquine derivative (AQD5) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (80 %) | NA | 24680954 |
DrugRepV_7074 | Amodiaquine derivative (AQD6) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (100 %) | NA | 24680954 |
DrugRepV_7075 | Amodiaquine derivative (AQD7) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (100 %) | NA | 24680954 |
DrugRepV_7076 | Amodiaquine derivative (AQD8) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (60 %) | NA | 24680954 |
DrugRepV_7077 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (50 %) | Approved | 24680954 |
DrugRepV_7078 | Amodiaquine derivative (AQD1) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_7079 | Amodiaquine derivative (AQD2) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_7080 | Amodiaquine derivative (AQD3) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_7081 | Amodiaquine derivative (AQD4) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_7082 | Amodiaquine derivative (AQD5) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_7083 | Amodiaquine derivative (AQD6) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_7084 | Amodiaquine derivative (AQD7) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_7085 | Amodiaquine derivative (AQD8) | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_7087 | Chloroquine Mustard | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_7088 | Chloroquine ethyl phenyl Mustard | Antiparasitic products, Insectisides and Repellents | Malaria | West Nile virus | NA | | Plaque assay | Decrease (50 %) | NA | 24680954 |
DrugRepV_7102 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | Yellow fever virus | 17D | | Plaque assay | Decrease (5.3 Log) | Approved, Investigational, Vet approved | 26752081 |
DrugRepV_7264 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Japanese encephalitis virus | Nakayama | | Flow cytometry | Decrease (85 %) | Investigational | 16309754 |
DrugRepV_7337 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Japanese encephalitis virus | P3 | | Plaque assay | Decrease (2 log %) | Approved | 24348901 |
DrugRepV_7340 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Japanese encephalitis virus | P3 | | Immunoflourescence assay | Decrease (30 %) | Approved | 24348901 |
DrugRepV_7343 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Japanese encephalitis virus | P3 | | Luminescence assay | Decrease (50 %) | Approved | 24348901 |
DrugRepV_7475 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | West Nile virus | New York | | Visual assay | Decrease (50 %) | Investigational | 12076755 |
DrugRepV_7476 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | West Nile virus | Uganda strain B 956 | | Visual assay | Decrease (50 %) | Investigational | 12076755 |
DrugRepV_7478 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | West Nile virus | New York | | NR assay | Decrease (50 %) | Investigational | 12076755 |
DrugRepV_7479 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | West Nile virus | Uganda strain B 956 | | NR assay | Decrease (50 %) | Investigational | 12076755 |
DrugRepV_7534 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | C-Tan-nCoV Wuhan strain 01 | NA | RT-PCR | Decrease (50 %) | Approved | 32150618 |
DrugRepV_7535 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | C-Tan-nCoV Wuhan strain 01 | NA | RT-PCR | Decrease (50 %) | Approved | 32150618 |
DrugRepV_7536 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Immunofluorescence | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7537 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Immunofluorescence | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7543 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | C-Tan-nCoV Wuhan strain 01 | NA | RT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7544 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | C-Tan-nCoV Wuhan strain 01 | NA | RT-PCR | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7546 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | Wuhan/WIV04/2022 | NA | qRT-PCR/ NP expression/Immunofluorescence | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7547 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | Wuhan/WIV04/2022 | NA | qRT-PCR/ NP expression/Immunofluorescence | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7552 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | SARS Coronavirus-2 | Wuhan/WIV04/2020 | NA | qRT-PCR/ NP expression/Immunofluorescence | Decrease (50 %) | Approved, Investigational, Vet approved | 32438446 |
DrugRepV_7553 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | SARS Coronavirus-2 | Wuhan/WIV04/2020 | NA | qRT-PCR/ NP expression/Immunofluorescence | Decrease (90 %) | Approved, Investigational, Vet approved | 32438446 |
DrugRepV_7566 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Immunofluorescence | Decrease (50 %) | Approved, Investigational | 32438446 |
DrugRepV_7567 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Immunofluorescence | Decrease (90 %) | Approved, Investigational | 32438446 |
DrugRepV_7569 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | C-Tan-nCoV Wuhan strain 01 | NA | RT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7570 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | C-Tan-nCoV Wuhan strain 01 | NA | RT-PCR | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7571 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Immunofluorescence | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7572 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Immunofluorescence | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7579 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | WA-1 strain - BEI ; NR-52281 | NA | Plaque assay / TCID50/ qRT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7580 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | WA-1 strain - BEI ; NR-52281 | NA | Plaque assay / TCID50/ qRT-PCR | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7581 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Immunofluorescence | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7582 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Immunofluorescence | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7583 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | WA-1 strain - BEI ; NR-52282 | NA | Plaque assay / TCID50/ qRT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7584 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | SARS Coronavirus-2 | Australia/VIC01/2020 isolate) | NA | RT-PCR | Decrease (50 %) | Approved, Investigational, Vet approved | 32438446 |
DrugRepV_7585 | Ivermectin | Antiparasitic products, Insectisides and Repellents | Intestinal strongyloidiasis | Onchocerciasis | SARS Coronavirus-2 | Australia/VIC01/2020 isolate) | NA | RT-PCR | Decrease (90 %) | Approved, Investigational, Vet approved | 32438446 |
DrugRepV_7596 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | WA-1 strain - BEI ; NR-52281 | NA | Plaque assay / TCID50/ qRT-PCR | Decrease (50 %) | Approved, Investigational | 32438446 |
DrugRepV_7597 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | WA-1 strain - BEI ; NR-52281 | NA | Plaque assay / TCID50/ qRT-PCR | Decrease (90 %) | Approved, Investigational | 32438446 |
DrugRepV_7608 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7609 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Cytopathic effect (CPE) assay | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7615 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | WA-1 strain - BEI ; NR-52290 | NA | Plaque assay / TCID50/ qRT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7616 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | WA-1 strain - BEI ; NR-52290 | NA | Plaque assay / TCID50/ qRT-PCR | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7654 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | WA-1 strain - BEI ; NR-52285 | NA | Plaque assay / TCID50/ qRT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7663 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | | NA | NA | Decrease (50 %) | Approved | 32344449 |
DrugRepV_7672 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 32511355 |
DrugRepV_7674 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 32511355 |
DrugRepV_7675 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 32511355 |
DrugRepV_7688 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | SARS Coronavirus-2 | | NA | NA | Decrease (50 %) | Approved | 32577649 |
DrugRepV_7779 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | SARS Coronavirus-2 | NA | NA | NA | Decrease (50 %) | Approved | 32687696 |
DrugRepV_7780 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | NA | NA | NA | Decrease (50 %) | Approved | 32687696 |
DrugRepV_7781 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | NA | NA | NA | Decrease (50 %) | Approved | 32687696 |
DrugRepV_7782 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | nCoV-2019BetaCoV/Wuhan/WIV04/2019 | NA | qRT-PCR | Decrease (50 %) | Approved | 32194981 |
DrugRepV_7783 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | nCoV-2019BetaCoV/Wuhan/WIV04/2019 | NA | qRT-PCR | Decrease (50 %) | Approved | 32194981 |
DrugRepV_7786 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | SARS Coronavirus-2 | SARS-CoV-2/Leiden-0002 | NA | qRT-PCR | Decrease (50 %) | Investigational | 32513797 |
DrugRepV_7809 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | Approved | 17663539 |
DrugRepV_7811 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | Middle East respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | Approved, Investigational, Vet approved | 32725286 |
DrugRepV_7812 | Tizoxanide | Antiparasitic products, Insectisides and Repellents | Crytosporidiosis and Giardiasis | Middle East respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | Approved, Investigational, Vet approved | 32725286 |
DrugRepV_7976 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S2.1 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7977 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S2.2 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7978 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S2.3 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7979 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S3 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7980 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S4.1 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7981 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S4.3 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7982 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S5 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7983 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S7 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7984 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S8 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_7985 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | Chikungunya virus | S9 | NA | CPE reduction assay | Decrease (50 %) | Investigational | 32191995 |
DrugRepV_8134 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Vaccinia virus | NA | | NA | Decrease (43.7 %) | Approved | 32708182 |
DrugRepV_8334 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | Experimental | NA | Viral inhibition assay | Decrease (50 %) | Approved | 32285930 |